Mathematics and Biology (the Pharma Vision)

I began this blog almost exactly three years ago. My goal was two-fold: first, to demonstrate thought leadership in an area in which I was then founding a company; and, second, to have a demonstrated track-record rather than a picture-perfect pitch-deck. This latter is clearly a sub-goal of the first.

In those early days, I began a series of articles on Mathematics and Biology. I began with a comparison of the two fields. From there I moved on to discussing the people and skills involved, essentially why mathematicians so rarely do biology. I then discussed the outlier which is bioinformatics. I had two further articles planned in the series, after which point I wanted to attempt a synthesis. The missing articles are on the Microbiome and Quantitative Systems Pharmacology (QSP). These will remain missing articles for now, time has moved on and my thoughts on all of these topics have progressed enormously.

A few weeks ago I published a futurecast about using virtual patient’s for pharma drug development. There was a key idea buried in that article which in essence is my current synthesis perspective on mathematics and biology. I want to highlight this idea here and flesh it out slightly.

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